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[nanoPost]燬uFET Based Either Implantable or Non-Invasive (Bio)Transducer of Nerve Impulses

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Research Centre Ukraine

The main objective of my nanotechnology activity is to combine the bioelectric nature of nerve impulses and synaptic currents between neighboring neurons with body-temperature pick-up  coil and zero resistance input of the superconducting field effect transistor (SuFET)  device in order to obtain most advantageous organism (living being)- machine interface. The implantable and non-invasive variants of the device are defined by the type of contacting pick-up coils  and/or SuFET channel(s) with nerve impulses and/or synaptic currents.

For more details see:
R. Sklyar, A SuFET Based Either Implantable or Non-Invasive (Bio)Transducer of Nerve Impulses, 13th International Symposium on Measurement and Control in  Robotics- Toward Advanced
Robots: Design, Sensors, Control and Applications - ISMCR'03, Madrid, Spain, 11-12 Dec., 2003, pp. 121-126.

Catalysis- Electronic noses and tongues.
Superconducting Organic and CNT FETs as a Biochemical Transducer (SuFETTr).
There are different kinds of transducers/sensors for picking up nerve impulses (NIs): room-tempereture and superconducting, external and implantable. Development of such devices is increasing the penetration into bioprocess while simultaneously simplifying the exploitation of the measuring systems in order to bring them closer to the wide range of applications. For this reason the magnetometer with a room-temperature pickup coil
(PC) (without using the toroidal core) for detecting signals, which can clearly be detected in higher frequency range, was developed in order to simplify the SQUID system. The PC is set outside the cryostat and is connected to the input coil of the SQUID or a channel of superconducting FET (SuFET). At frequencies higher than 20 Hz the noise decreases as 1/f function and then reaches a high flat noise at 2kHz as 200 fT/併Hz. On the other hand, implantable into nerve fiber transducers are evolving from the ordinary Si-chip microelectronics devices into superconducting and nanodevices.
The recent achievements in nanoelectronics can be regarded as a further step in the progress of BS transdution. They give us the possibility to create the most advanced and universal device on the basis of known micro systems. Such a sensor/transducer is suitable for picking up biosignals (BSs)- NIs, electrically active (ionized) molecules and the base-pair recognition event in DNA sequences- and transforming it into recognizable information in the form of electric voltage, or a concentration of organic or chemical substances. Moreover, this process can be executed in reverse. Substances and/or voltages influence BSs, thereby controling or creating them (BSs).
Application variety of the novel superconducting, organic and CNT FETs allows us to design transducers of BSs (nerve, DNA, etc.) that transduce them into different quantities, including electric voltage, density of chemical and biomolecules. On the other hand, the said BSs can be controlled by the applied electrical signals, or bio and chemical mediums. The range of picked up BSs varies from
0.6 nA to 10 礎 with frequencies from 20 to 2000 Hz. The output signal lies in the range of 𤒍V, (70)10E17/cmE3 molecules and 210 pH. The substantial impediment for realization of the advanced SuFETTrs is deficient investigation in the direction of superconduction the said FETs both in theory and experimentally.

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Edited by: Andy     


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