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[nanoPost] Synthesis and processing of nanoparticles and nanoporous materials

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University UK

 

My research deals with materials and processes at colloidal (nanometer to micrometer) length scales. The focus of my recent work related to nanotechnology has been mainly on synthesis and processing of nanoparticles and nanoporous materials. I

 

 My main current activities related to nanoparticles and nanostructured materials are in the following areas:
1) Development of novel nanoporous materials for advanced separations a) design of novel bioseparations media based on particulate gels with controlled interfacial, transport and mechanical properties, prepared by aggregation of dispersed polymeric nanoparticles  b) synthesis of nanoparticle based zeolite membranes for more efficient separations


 2) Polymer-clay nanocomposites Control of microstructure evolution during in-situ polymerization for preparation of polymer-clay nanocomposites with superior barrier and fire resistance properties

 

3) Particle formation processes a) scale-up of a process for formation of protein-coated microcrystals for drug delivery   b) development of continuous mini and microreactor technologies for intensification of nanoparticle formation processes

 

My further research interests include: - deposition and fouling in nanoparticle dispersions (surface spectroscopic techniques) - colloidal stability and aggregation of nanoparticles and proteins (light scattering techniques) - nanoparticle aggregation and breakage in turbulent flows (population balance modelling)

The best commercial prospects for the next 3-10 years in what you are doing and where it could be best applied.  a) New porous media for chromatographic bioseparations, in situ extraction of metabolic intermediates from cell cultures, and supports for solid state synthesis. These novel materials will be based on polymeric nanoparticles assembled into porous monoliths or beads with controlled transport, mechanical properties, interfacial and chemical properties allowing to be tuned to particular applications (such as monoclonal antibody separation).  b) New mini and microreactor technologies for continuous production of functional nanoparticles for biomedical applications and drug delivery. Accurate control of composition and mixing in precipitation and crystallisation of nanoparticles allows tuning of particle size, morphology and composition (such as core-shell or artificial spores) for particular drug delivery applications.

  
     
Edited by: Andy     


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