[nanoPost] biocompatibility tests based on immunofluorescence microscopy combined with tissue c

Research Centre Romania

We are a basic research institute specialized in proteins and
biocompatibility tests. Thus,
a)We have developed biocompatibility tests based on immunofluorescence  microscopy combined with tissue culture technology. By these tests we can  assess the biocompatibility of nanomaterials with human living cells, for nanomaterials to be used as implants or biosensors.
b)We can produce recombinant proteins for nanotechnological purposes.
c) We have developed a liposome technology able to include small
molecules, such as iminosugars in the aqueous cavity of liposomes(Costin GE,
Trif M, Nichita N, Dwek RA, Petrescu SM.pH-sensitive liposomes are
efficient carriers for endoplasmic reticulum-targeted drugs in mouse
melanoma cells. Biochem Biophys Res Commun. 2002 May 10;293(3):918-23).