[nanoPost] Fluoropolymer materials platform

Company USA

The company utilizes its proprietary product platform to commercialize high-value products with nano-precision ranging from the materials to the life sciences sectors. The  product platform is a breakthrough method that utilizes technologies adapted from the microelectronics industry for the fabrication of engineered shape and size-specific nanomaterials.

This platform, enabled by the company's proprietary  materials, allows the company to address unmet market needs through precise design and commercial-scale manufacturing of micro- and nano-structured materials, including discrete particles, arrays of particles and patterned films. 

Engineered Drug Therapies

In the Life Sciences, the platform provides nano-replication technology to design and manufacture discrete nanoparticles of pure drug, drug and excipients, or drug in an organic carrier.

The unique properties of the  platform enable the company to control shape, size, modulus, surface functionality, and chemistry of nanoparticles, in order to optimize pharmacokinetics and pharmacodynamics of active pharmaceutical ingredients.

Active Pharmaceutical Ingredients (API)

It is well known that many drug compounds in early stages of development and on the market today have poor aqueous solubility. For this reason, pharmaceutical companies are often forced to include harmful solubilizing agents with the drug compound, which may produce suboptimal side-effects, or discard a large number of otherwise promising compounds. Alternatively, some products are launched that have undesirable dosing requirements such as large size and/or multiple tablets.

The platform, on the other hand, provides the unique ability to control nanoparticle size, shape, and composition which offers a promising solution for overcoming solubility-related issues and developing therapeutics with improved safety, efficacy and dosing requirements.

Engineered Drug Therapies
The company's technology is revolutionizing the development of engineered drug therapies for the diagnosis and treatment of human disease.

Particles fabricated from the  platform can be made of a wide variety of materials, generated in any size and shape, infused with any cargo and surface-functionalized with any ligand. The platform uniquely allows for tailored drug loading and release capabilities.

The company is the only company in the world that can independently design these attributes to create engineered drug therapies. This level of design control represents a paradigm shift for the pharmaceutical and biotechnology industries.

Platform produced particles can be comprised of  
 

- Conducting polymers 
 
- Biodegradable polymers 
 
- Hydrogels 
 
- Natural products 
 
- Small organic and inorganic materials 
 
- Active pharmaceutical ingredients 

 
Platform produced particles can incorporate cargos including inorganics, imaging agents,oligonucleotides, siRNA fragments, proteins, active pharmaceutical ingredients and viral vectors.

 
Platform produced particle surfaces can be functionalized with ligands, fluorescent dyes, cell-penetrating peptides, cell-targeting peptides,antibodies, proteins and other materials
 

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