[nanoPost] Nanoencapsulation for delivery of active ingredients

Company Israel

Using patented, clear silica microcapsules, the company precisely controls the delivery rate of active ingredients, significantly improving both efficacy and tolerability.

With the company's unique, state-of-the-art process, a wide range of active pharmaceutical ingredients (APIs) can be encased. The silica microcapsules can be fine-tuned to provide optimal release properties to wide range of actives, including liquids, hydrophobic materials and solids with poor water-solubility.

Patent-protected technology for modular construction of the capsule shell enables us to control the capsule size and structure as well as porosity. As a result, we can design capsules that are as big as needed or as small as a few nanometers in diameter, with release rates ranging from non-leachable capsules to precisely timed release.

Silica, an inorganic material, is recognized by the FDA as a safe excipient for topical and oral drugs. Cost-effective to manufacture and easy to formulate, Sol-Gel microcapsules feature capabilities superior to organic polymers.

Technology
 
State of the Art Drug Delivery  
The company has developed a unique process that enables a wide range of active ingredients to be encapsulated at room temperature. The silica microcapsules can be fine-tuned to provide optimal release properties for numerous actives including liquids, hydrophobic materials, and solids with poor water-solubility.

 
Technology Breakthrough
We have devised a breakthrough sol-gel based micro-encapsulation technology in which a transparent silica shell is formed around entrapped actives.
        

Patent-protected technology for modular construction of the capsule shell enables us to precisely control the capsule size and structure as well as properties such as porosity. As a result, we can design capsules that are as large as needed or as small as a few nanometers in diameter with a release rate ranging from non-leachable capsules to timed release.
 

The technologies commonly used for the encapsulation and delivery of active ingredients use organic polymers as embedding materials. Our proprietary technology, which uses inorganic silica gel, offers technological and regulatory advantages. Today, we have commercialized an array of encapsulation techniques that enable us to rapidly develop and produce high-volume commercial applications to effectively address market requirements.