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[nanoPost] Anti-microbial silver nanoparticles

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  University UK The use of silver and silver compounds for the prevention of microbial growth has been exploited in the medical arena for several years. The application of a silver coating to prevent the build up of bio films and the subsequent infections of implants is widespread as is the use of silver in wound dressings. The University has technology in this area that is available as a licensing opportunity.
The technology makes use of supercritical fluids to impregnate polymeric substrates with nanoparticles of silver. This technology is extremely versatile. The Silver nanoparticles are able to imbue the polymeric matrix with long term broad-spectrum anti-microbial properties. The use of supercritical fluids provides a technology that allows a wide variety of polymers to be treated and decreases the toxic waste products of traditional treatments.
Mode of action
Silver Ions bind to the sulfhydryl groups on proteins leading to the protein becoming denatured. The advantage of impregnating a material with silver nanoparticles as opposed to a traditional coating is the anti-microbial effects are long lasting and can be used in regions where the surface is exposed to a flowing liquid; the silver ions on the surface are replenished by the particles with in the material.
 
     
Edited by: Andy     


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